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Diagnostic Tools
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Bioreclamation offers a full line of products that can be used for diagnostic and assay applications.
Human Anti Mouse Antibody (HAMA)
Human Anti Mouse Antibody (HAMA) is derived from a proprietary Human Cell Line, and can be used as an alternative for serum samples that are positive for HAMA. You will no longer have to search for elevated serum samples that are “positive” for HAMA. You will know exactly what quantity and what HAMA immunoglobulins are interfering in your assay. You will now be able to empirically determine the extent of inference produced by Human Anti Mouse Antibody in any or all of your immunoassays. A stock solution of HAMA, added to a negative serum sample, can now be used to validate the HAMA interference in all your immunoassays.
Immunoglobulin Inhibiting Reagent (IIR)
A unique reagent to prevent heterophilic antibody interference in immunoassays, Immunoglobulin Inhibiting Reagent (IIR) is a formulation of immunoglobulins that is specifically targeted against heterophilic antibodies to block their interference in immonoassays. IIR is not precipitated IgG. Because of it’s unique formulation and it’s putiry (>96%), IIR may be used at extremely low concentrations without any effect on dilutions or recovery.
IIR has an extremely high binding affinity which enables it to inhibit the action of human heterophilic antibodies. The affinity value of human heterophilic antibodies is in the order of 106 Litres/Mol. Immunoglobulin Inhibiting Reagent (IIR) has a binding affinity which exceeds 109 Litres/Mol. This greatly enhanced binding affinity ensures that heterophilic interference is virtually eliminated.
Human IgE (Monoclonal)
This product is purified human IgE with kappa light chains produced in vitro from a monoclonal hybridoma.The purity of the human IgE is > 98%, tested by SDS-PAGE. As the IgE comes from a cell line, there is no contamination of antibodies of other isotypes.
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